Found 61 matching trials
A Study Evaluating the Long-term Safety and Efficacy of Elexacaftor/Tezacaftor/Ivacaftor in Cystic Fibrosis (CF) Particpants 6 Years and Older and F/MF Genotypes PHASE3 The study evaluates the long-term safety and efficacy of elexacaftor (ELX)/...
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Telethon Kids Institute
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Impact of Rifabutin on the Pharmacokinetics of Elexacaftor/Tezacaftor/Ivacaftor PHASE4 This is a prospective, single-center, fixed-sequence, nonrandomized, open-l...
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University of Southern California
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A Study to Assess the Effect of ELX/TEZ/IVA on Glucose Tolerance in Participants With Cystic Fibrosis (CF) PHASE3 This study was evaluate the effect of elexacaftor (ELX)/tezacaftor (TEZ)/iv...
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Royal Adelaide Hospital
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CFTR Modulators in Pregnancy and Postpartum N/A Observational study on women with Cystic Fibrosis treated with CFTR modulat...
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Stockholm CF center
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Evaluation of Long-term Safety and Efficacy of ELX/TEZ/IVA in Cystic Fibrosis Participants 12 Months of Age and Older PHASE3 The purpose of the study is to evaluate the long-term safety, tolerability,...
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Active Not Recruiting
Location
The Kids Research Institute Australia
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Real World Clinical Outcomes With Novel Modulator Therapy Combinations in People With CF (RECOVER) PHASE4 RECOVER is a prospective, multicenter observational study designed to measu...
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Active Not Recruiting
Location
Children's Health Ireland at Crumlin
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Glucose Metabolism in Cystic Fibrosis Related Diabetes (CFRD) N/A The study aims to test whether use of CFTR modulators (ETI) improves fastin...
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Enrolling By Invitation
Location
University of Alabama at Birmingham
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Effect of One Year Elexacaftor-tezacaftor-ivacaftor Treatment N/A The development of CFTR (cystic fibrosis conductance transmembrane regulato...
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Hopitaux Universitaires de Strasbourg
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Daily Monitoring of Respiratory Symptoms and Spirometry During ETI Treatment in Persons With Cystic Fibrosis. N/A The goal of this observational study is to provide optimal monitoring and s...
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Pharmacokinetics of Antibiotics in Patients With Cystic Fibrosis Trated With Elexacaftor/Tezacaftor/Ivacaftor (ETI) N/A Cystic fibrosis (CF) is associated with major pharmacokinetic and pharmacod...
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